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Is lack of habituation a biomarker of migraine? A critical perspective

2015

Processing of sensory stimuli has been supposed to be dysfunctioning in migraine. A basis for such abnormality has been identified in a defective ability to habituate to repetitive sensorial stimulation. Habituation, i.e. the way the nervous system attenuates response to repeated non noxious stimuli is a fundamental function of sensory systems, that allows appropriate adaptation of neural responses to the relevance of incoming stimuli. In humans, habituation can be studied by evoked potentials where it is indexed by a reduction of amplitude of the evoked response to repeated stimulation. After the first evidence by Schoenen et al in 1995[1] of reduced habituation to visual evoked potentials…

medicine.medical_specialtyNeurologybusiness.industryInvited Speaker PresentationClinical NeurologySensory systemStimulationGeneral Medicinemedicine.diseaseSomatosensory systemhabituationNeurology (clinical); Anesthesiology and Pain Medicine; habituation; migraineStimulus modalityAnesthesiology and Pain MedicineMigrainemedicineNoxious stimulusmigraineSettore MED/26 - NeurologiaNeurology (clinical)HabituationbusinessNeuroscience
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